News about Mass Spectrometry and related topics
Mittwoch, 7. November 2018
SLIM 2.0 - Structure for lossless ion manipulation
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Structures for lossless ion manipulation, abbreviated SLIM, is a special low cost technique that utilitzes drift time ion mobility. SLIM is ...
Samstag, 3. November 2018
Conductive polymer spray ionization
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This is an advancement of paper spray ionization selective for hydrophilic compounds. Traditionally, paper spray utilizes cellulose as...
Mittwoch, 31. Oktober 2018
FlashPack enables packing of 50cm columns with 2mircon particles in less than an one hour
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Usually column packing using sub micron particle requires packing pressures of sometimes more than 1000bars. Such workflows require specia...
Dienstag, 2. Oktober 2018
Ionic liquid matrices in MALDI MS
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I know that sometimes glyercol is used a liquid matrix in IR MALDI, but I have ever heard about Ionic Liquid Matrices (ILMs) before. These...
Sonntag, 16. September 2018
Ultra High Pressure Column Packing
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Ultra-high pressure HPLC can be one method to combat the high sample complexity of shot gun proteomics mixtures. During the years there ha...
Freitag, 7. September 2018
EvoSep One nanoLC - combines low pressure sample loading and offline gradient formation for reproducible proteomics measurements
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Usually reproducibility is a huge problem in nanoLC MS using an conventional 2-column setup utilizing sub-2µm solid core particles. Due ...
Donnerstag, 6. September 2018
FUNPET - half ion funnel, half ion carpet
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FUNPET is a hybrid ion funnel ion carpet MS interface. It combines the advantages on an classical stacked ring RF-only driven ion funnel a...
Freitag, 17. August 2018
In-solution, In-gel, FASP and S-Traping - a voyage through protein sample preparation
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When it comes sample preparation in bottom-up proteomics one likes to be as fast, as reproducible and as efficient as possible. Unfortun...
Mittwoch, 8. August 2018
In vivo TMT labelling
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Tandem Mass Tag (TMT) is a common technique for quantification of peptides at the MS2 level. The TMT is based on the reaction of the Primar...
Freitag, 3. August 2018
New features in skyline - LC-IMS-CID-MS and contaminations library
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There is a lot going on in the skyline world lately. Originally, open source software skyline from the MacCoss Lab which started out as...
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